Atopic diseases and oncopathology. What do they have in common? A review

The increasing prevalence of cancer worldwide has influenced the interest researchers to search for factors that may trigger oncogenesis in order prevent and treat cancer. There is a burning question, can allergic diseases cause or cancer? Numerous epidemiological studies have been conducted evaluated aspects relationship between occurrence cancers various localizations. results most these are inconsistent, both nature course disease variety localizations In this connection, two basic theories were suggested: theory immune surveillance inflammation. This review analyzed current scientific work estimate incidence neoplasms against background atopic diseases. analysis clinical shows inconsistent association Several an inverse risk, which supports [brain tumor (glioma), pancreatic cancer, colorectal non-Hodgkin's lymphoma, breast mouth throat, larynx]. At same time, number note positive confirms chronic inflammation (lung combined with bronchial asthma). lack unequivocal explanation testifies urgency long-term prospective aimed at studying risk combination subsequent development scale purpose patient stratification, screening, early detection programs new approaches treatment malignant neoplasms.